Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.47 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31127087 | 0.91 | KCNN2 (0.56) | KCNN2KCNN3ADORA2AADORA1ALOX15 | |
| SCHEMBL19686923 | 0.91 | KCNN2 (0.56) | KCNN2KCNN3ADORA2AADORA1ALOX15 | |
| SCHEMBL19686315 | 0.91 | KCNN2 (0.56) | KCNN2KCNN3ADORA2AADORA1ALOX15 | |
| SCHEMBL19686314 | 0.91 | KCNN2 (0.56) | KCNN2KCNN3ADORA2AADORA1ALOX15 | |
| SCHEMBL19686913 | 0.90 | KCNN2 (0.44) | KCNN2KCNN3ADORA2AADORA1ALOX15 | |
| SCHEMBL19686510 | 0.85 | KCNN2 (0.51) | KCNN2KCNN3ADORA2AADORA1ALOX15 | |
| SCHEMBL19687072 | 0.84 | KCNN2 (0.53) | KCNN2KCNN3ADORA2AADORA1ALOX15 | |
| SCHEMBL19686933 | 0.82 | KCNN2 (0.57) | KCNN2KCNN3ADORA2AADORA1ALOX15 | |
| SCHEMBL19687322 | 0.81 | KCNN2 (0.40) | KCNN2KCNN3ADORA2AADORA1LMNA | |
| SCHEMBL21143991 | 0.81 | KCNN3 (0.56) | KCNN2KCNN3ADORA2AADORA1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017139697-A9 | BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA | SYNLOGIC, INC. (US) | 2017-12-07 | — | — | WO | disclosed |