Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.40 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 11/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19686295 | 0.81 | KCNN2 (0.47) | KCNN2KCNN3ADORA2AADORA1LMNA | |
| SCHEMBL19687321 | 0.81 | IDH1 (0.47) | IDH1 | |
| SCHEMBL19687323 | 0.81 | — | — | |
| SCHEMBL19686305 | 0.79 | KCNN2 (0.53) | KCNN2KCNN3IDH1ADORA2AADORA1 | |
| SCHEMBL21144444 | 0.79 | IDH1 (0.46) | KCNN2KCNN3IDH1 | |
| SCHEMBL19686913 | 0.79 | KCNN2 (0.44) | KCNN2KCNN3ADORA2AADORA1LMNA | |
| SCHEMBL19686522 | 0.77 | KCNN2 (0.58) | KCNN2KCNN3IDH1ADORA2AADORA1 | |
| SCHEMBL19687072 | 0.77 | KCNN2 (0.53) | KCNN2KCNN3IDH1ADORA2AADORA1 | |
| SCHEMBL19686589 | 0.77 | KCNN3 (0.52) | KCNN2KCNN3IDH1ADORA2AADORA1 | |
| SCHEMBL19686510 | 0.76 | KCNN2 (0.51) | KCNN2KCNN3ADORA2AADORA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017139697-A9 | BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA | SYNLOGIC, INC. (US) | 2017-12-07 | — | — | WO | disclosed |