SCHEMBL1968632

SCHEMBL1968632

Fc1cccc(-c2nccc3ccccc23)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 1/20 0.57
ADORA2A P29274 2/20 0.51
KDM4E B2RXH2 4/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
MAPT P10636 2/20 0.50
KMT2A Q03164 2/20 0.50
GLA P06280 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
GPR55 Q9Y2T6 1/20 0.47
TRPA1 O75762 1/20 0.46
SCN9A Q15858 1/20 0.44
MAPK1 P28482 2/20 0.44
MAPK13 O15264 1/20 0.43
RAF1 P04049 1/20 0.43
MAPK12 P53778 1/20 0.43
MAPK11 Q15759 1/20 0.43
MAPK14 Q16539 1/20 0.43
PDE10A Q9Y233 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17343654 0.88 TDO2 (0.56) TDO2ADORA2AKDM4ENPC1RAB9A
SCHEMBL17449880 0.88 KDM4E (0.57) TDO2KDM4ENPC1RAB9AL3MBTL1
SCHEMBL29607745 0.88 KDM4E (0.57) TDO2KDM4ENPC1RAB9AL3MBTL1
SCHEMBL12157382 0.86 KDM4E (0.49) TDO2KDM4ENPC1RAB9AL3MBTL1
SCHEMBL11976496 0.86 TDO2 (0.47) TDO2KDM4ENPC1RAB9AL3MBTL1
SCHEMBL3141880 0.83 KDM4E (0.57) TDO2KDM4ENPC1RAB9AL3MBTL1
SCHEMBL18858280 0.81 KDM4E (0.46) TDO2KDM4ENPC1RAB9AL3MBTL1
SCHEMBL11976498 0.81 KDM4E (0.55) TDO2KDM4ENPC1RAB9AL3MBTL1
SCHEMBL17426492 0.81 KDM4E (0.51) TDO2KDM4ENPC1RAB9AL3MBTL1
SCHEMBL3391756 0.81 BCHE (0.54) ADORA2AKDM4ENPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8911881-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-16 US disclosed
US-8911881-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-16 US disclosed
EP-2492276-B1 METAL COMPLEX, POLYMER, AND ELEMENT OBTAINED USING SAME SUMITOMO CHEMICAL CO (JP) 2014-10-08 EP disclosed
US-8846920-B2 Metal complexes MERCK PATENT GMBH (DE) 2014-09-30 US disclosed
US-8846920-B2 Metal complexes MERCK PATENT GMBH (DE) 2014-09-30 US disclosed
US-8846920-B2 Metal complexes MERCK PATENT GMBH (DE) 2014-09-30 US disclosed
EP-2492276-A1 METAL COMPLEX, POLYMER, AND ELEMENT OBTAINED USING SAME Sumitomo Chemical Company, Limited (JP) 2012-08-29 EP disclosed
US-20120205585-A1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-16 US disclosed
US-20120205585-A1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-16 US disclosed
CN-102627671-A Metal complexes MERCK PATENT GMBH 2012-08-08 CN disclosed
US-7521130-B2 Organic electroluminescent display device having superior characteristics at high temperature SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2009-04-21 US disclosed
CN-100375749-C Luminescence device and display apparatus CANON KK (JP) 2008-03-19 CN disclosed
US-20070034863-A1 fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon UDC IRELAND LIMITED (IE) 2007-02-15 US disclosed
US-20070034863-A1 fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon UDC IRELAND LIMITED (IE) 2007-02-15 US disclosed
US-20070034863-A1 fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon UDC IRELAND LIMITED (IE) 2007-02-15 US disclosed
CN-1285601-C Light emitting device and display CANON KK (JP) 2006-11-22 CN disclosed
CN-1860202-A Metal complexes COVION ORGANIC SEMICONDUCTORS (DE) 2006-11-08 CN disclosed
EP-1675929-A1 METAL COMPLEXES MERCK PATENT GmbH (DE) 2006-07-05 EP disclosed
CN-1781925-A Luminescence device and display apparatus CANON KK (JP) 2006-06-07 CN disclosed
WO-2005033244-A1 METAL COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2005-04-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120205585-A1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE USING THE SAME HDAC10, EMG1, PRMT1 TDO2 1601/4885ADORA2A 4310/4885KDM4E 1254/4885
US-20070034863-A1 fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon NISCH, CISD1, AFF1 TDO2 176/4885ADORA2A 3838/4885KDM4E 3959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.