Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 5/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18327498 | 0.86 | MAPT (0.53) | KDM4ENPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL17413794 | 0.86 | MAPT (0.53) | KDM4ENPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL29607745 | 0.86 | KDM4E (0.57) | KDM4ENPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL17449880 | 0.86 | KDM4E (0.57) | KDM4ENPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL18858309 | 0.85 | MAPT (0.51) | KDM4ENPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL17945790 | 0.84 | KDM4E (0.50) | KDM4ENPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL18327514 | 0.84 | MAPT (0.50) | KDM4ENPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL18325294 | 0.82 | L3MBTL1 (0.47) | KDM4ENPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL17932557 | 0.82 | KDM4E (0.46) | KDM4ENPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL17944664 | 0.82 | HTR2B (0.50) | KDM4ENPC1RAB9AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230403927-A1 | AROMATIC COMPOUNDS | UDC IRELAND LTD (IE) | 2023-12-14 | — | — | US | disclosed |
| US-20230403927-A1 | AROMATIC COMPOUNDS | UDC IRELAND LTD (IE) | 2023-12-14 | — | — | US | disclosed |
| US-11800787-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2023-10-24 | — | — | US | disclosed |
| US-11800787-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2023-10-24 | — | — | US | disclosed |
| EP-3160976-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-24 | — | — | EP | disclosed |
| US-20170141329-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-05-18 | — | — | US | disclosed |
| US-20170141329-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230403927-A1 | AROMATIC COMPOUNDS | TYR, CTCF, MITF | KDM4E 1344/4885NPC1 3191/4885RAB9A 2503/4885 |
| US-20170141329-A1 | METAL COMPLEXES | AP1M1, SOD1, AP3M1 | KDM4E 3544/4885NPC1 3855/4885RAB9A 1927/4885 |
| US-11800787-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | KDM4E 3544/4885NPC1 3855/4885RAB9A 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.