SCHEMBL19686897

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21143909	0.91	IDH1 (0.47)	IDH1IDH2FABP4FABP5
	SCHEMBL21143660	0.90	IDH1 (0.37)	IDH1CDC7CHEK1MAPK13PDPK1
	SCHEMBL31127343	0.90	IDH1 (0.37)	IDH1CDC7CHEK1MAPK13PDPK1
	SCHEMBL19686338	0.90	IDH1 (0.51)	IDH1IDH2ADORA2AFABP4FABP5
	SCHEMBL31127090	0.88	IDH1 (0.40)	IDH1CDC7CHEK1MAPK13PDPK1
	SCHEMBL21143735	0.88	IDH1 (0.40)	IDH1CDC7CHEK1MAPK13PDPK1
	SCHEMBL21165966	0.87	IDH1 (0.49)	IDH1IDH2ADORA2AFABP4FABP5
	SCHEMBL19686995	0.87	IDH1 (0.49)	IDH1IDH2ADORA2AFABP4FABP5
	SCHEMBL31127091	0.87	IDH1 (0.49)	IDH1IDH2ADORA2AFABP4FABP5
	SCHEMBL21143951	0.86	IDH1 (0.48)	IDH1IDH2ADORA2AFABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.