Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1318655 | 0.79 | POLB (0.42) | S1PR2ALDH1A1 | |
| SCHEMBL19708844 | 0.79 | S1PR2 (0.35) | S1PR2ALDH1A1 | |
| SCHEMBL19708732 | 0.78 | MEN1 (0.38) | S1PR2 | |
| SCHEMBL20614567 | 0.74 | ALDH1A1 (0.30) | ALDH1A1GAAPKMMAPK1 | |
| SCHEMBL9883847 | 0.74 | TSHR (0.44) | ALDH1A1GAAMAPK1 | |
| SCHEMBL19708843 | 0.73 | MAPT (0.49) | ALDH1A1GAAMAPK1 | |
| SCHEMBL21166232 | 0.73 | CYP1A2 (0.57) | ALDH1A1GAAPKM | |
| SCHEMBL19687410 | 0.73 | KDM4E (0.40) | ALDH1A1GAA | |
| SCHEMBL19708851 | 0.72 | S1PR2 (0.34) | S1PR2 | |
| SCHEMBL19687284 | 0.70 | HSP90AA1 (0.32) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017139697-A9 | BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA | SYNLOGIC, INC. (US) | 2017-12-07 | — | — | WO | disclosed |