Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 16/20 | 0.39 |
| ▸ | IDH2 | P48735 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GPR39 | O43194 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19686267 | 0.79 | KCNN2 (0.48) | IDH1KDM4EMAPK1 | |
| SCHEMBL19686523 | 0.73 | IDH1 (0.44) | IDH1IDH2 | |
| SCHEMBL19687150 | 0.73 | IDH1 (0.39) | IDH1IDH2 | |
| SCHEMBL19687174 | 0.73 | IDH1 (0.39) | IDH1IDH2 | |
| SCHEMBL19686622 | 0.72 | KCNN2 (0.38) | IDH1IDH2KDM4EMAPKAPK2 | |
| SCHEMBL19687152 | 0.71 | IDH1 (0.38) | IDH1IDH2 | |
| SCHEMBL19687151 | 0.71 | IDH1 (0.38) | IDH1IDH2 | |
| SCHEMBL19686686 | 0.69 | IDH1 (0.37) | IDH1IDH2GPR39 | |
| SCHEMBL19687218 | 0.68 | IDH1 (0.38) | IDH1IDH2 | |
| SCHEMBL19687411 | 0.68 | IDH1 (0.39) | IDH1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017139697-A9 | BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA | SYNLOGIC, INC. (US) | 2017-12-07 | — | — | WO | disclosed |