Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | AGXT | P21549 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KIF11 | P52732 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18644936 | 0.91 | NPC1 (0.36) | NPC1RAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL24799970 | 0.91 | NPC1 (0.36) | NPC1RAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL8652255 | 0.91 | NPC1 (0.36) | NPC1RAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL19782363 | 0.89 | CYP1A2 (0.40) | TAAR1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL15510613 | 0.84 | ACHE (0.40) | NPC1RAB9AALDH1A1KDM4ETDP1 | |
| SCHEMBL19199109 | 0.84 | KDM4E (0.37) | NPC1RAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL27269092 | 0.84 | MAPT (0.33) | NPC1RAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL27269296 | 0.84 | MAPT (0.33) | NPC1RAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL27403520 | 0.84 | HPGD (0.33) | NPC1RAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL27403698 | 0.84 | HPGD (0.33) | NPC1RAB9AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024005461-A1 | NOVEL LINKER COMPOUND AND LIGAND-DRUG CONJUGATE THEREFOR | 주식회사 트리오어 | 2024-01-04 | — | — | WO | disclosed |
| EP-3827849-A1 | PET-IMAGING IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2021-06-02 | — | — | EP | disclosed |
| EP-3224277-B1 | NOVEL PD-L1 BINDING POLYPEPTIDES FOR IMAGING | BRISTOL MYERS SQUIBB CO (US) | 2020-08-26 | — | — | EP | disclosed |
| WO-2017210335-A1 | IMAGING METHODS USING 18F-RADIOLABELED BIOLOGICS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |