SCHEMBL8652255

SCHEMBL8652255

Cc1ccc(SOCCOCCOSc2ccc(C)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 3/20 0.35
ACHE P22303 1/20 0.35
MAPT P10636 5/20 0.34
HPGD P15428 4/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
L3MBTL1 Q9Y468 3/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DNMT1 P26358 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24799970 1.00 NPC1 (0.36) NPC1RAB9AALDH1A1TDP1ACHE
SCHEMBL18644936 1.00 NPC1 (0.36) NPC1RAB9AALDH1A1TDP1ACHE
SCHEMBL15510613 0.93 ACHE (0.40) NPC1RAB9AALDH1A1TDP1ACHE
SCHEMBL27269296 0.92 MAPT (0.33) NPC1RAB9AALDH1A1TDP1MAPT
SCHEMBL19199109 0.92 KDM4E (0.37) NPC1RAB9AALDH1A1TDP1ACHE
SCHEMBL27403698 0.92 HPGD (0.33) NPC1RAB9AALDH1A1TDP1MAPT
SCHEMBL27403520 0.92 HPGD (0.33) NPC1RAB9AALDH1A1TDP1MAPT
SCHEMBL27269092 0.92 MAPT (0.33) NPC1RAB9AALDH1A1TDP1MAPT
SCHEMBL12944276 0.91 MEN1 (0.39) NPC1RAB9AALDH1A1MAPTHPGD
SCHEMBL19687560 0.91 TAAR1 (0.35) NPC1RAB9AALDH1A1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0688759-B1 Alpha-resorcylic acid ester derivatives and recording materials incorporating them FUJI PHOTO FILM CO LTD (JP) 1998-10-07 EP disclosed
US-5693374-A Alpha-resorcyclic acid ester derivatives and recording materials using the same FUJI PHOTO FILM CO., LTD. (JP) 1997-12-02 US disclosed
EP-0688759-A1 Alpha-resorcylic acid ester derivatives and recording materials incorporating them FUJI PHOTO FILM CO., LTD. (JP) 1995-12-27 EP disclosed