Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16090778 | 0.79 | KMT2A (0.41) | KMT2ACNR1LMNARXFP1KDM4E | |
| SCHEMBL19687583 | 0.77 | MEN1 (0.43) | KMT2AMEN1HSD17B10LMNATP53 | |
| SCHEMBL16090777 | 0.77 | KDM4E (0.39) | KMT2AMEN1LMNATP53RXFP1 | |
| SCHEMBL16090775 | 0.73 | PARG (0.37) | — | |
| SCHEMBL806475 | 0.71 | RXFP1 (0.49) | KMT2AMEN1LMNATP53RXFP1 | |
| SCHEMBL29769066 | 0.71 | RXFP1 (0.49) | KMT2AMEN1LMNATP53RXFP1 | |
| SCHEMBL16031735 | 0.68 | NR1H2 (0.43) | — | |
| SCHEMBL3005494 | 0.67 | PTGDR2 (0.47) | KMT2AMEN1KDM4EALDH1A1GAA | |
| SCHEMBL21084047 | 0.67 | KMO (0.49) | KMT2AMEN1HSD17B10LMNARAB9A | |
| SCHEMBL21196908 | 0.67 | SCN7A (0.55) | HSD17B10KDM4EALDH1A1HPGDPLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |