Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PRF1 | P14222 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687581 | 0.87 | KDM4E (0.44) | MEN1KMT2ALMNARAB9AMAPK1 | |
| SCHEMBL19687624 | 0.77 | KMT2A (0.38) | MEN1KMT2AAS3MTLMNARAB9A | |
| SCHEMBL19687591 | 0.77 | MEN1 (0.43) | MEN1KMT2ARAB9ATSHRKDM4E | |
| SCHEMBL19687598 | 0.75 | RAB9A (0.35) | LMNARAB9ATSHRKDM4EMAPT | |
| SCHEMBL19687576 | 0.75 | RAB9A (0.35) | MEN1KMT2ALMNARAB9ATSHR | |
| SCHEMBL19687594 | 0.72 | ESR1 (0.40) | MEN1KMT2ALMNARAB9APOLB | |
| SCHEMBL19687577 | 0.72 | MEN1 (0.46) | MEN1KMT2ARAB9AMAPK1TSHR | |
| SCHEMBL19687579 | 0.71 | RAB9A (0.33) | MEN1KMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL19687586 | 0.70 | MEN1 (0.46) | MEN1KMT2ALMNAMAPK1TSHR | |
| SCHEMBL19687584 | 0.70 | PARG (0.39) | MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |