Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 8/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20631657 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL17871030 | 0.75 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL20631096 | 0.73 | ALDH1A1 (0.36) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL30852659 | 0.72 | L3MBTL1 (0.46) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL19687621 | 0.70 | ATR (0.37) | ALDH1A1MAPTKMT2AHSD17B10TSHR | |
| SCHEMBL9446210 | 0.70 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL20609732 | 0.70 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL20049782 | 0.69 | ALDH1A1 (0.57) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL17871020 | 0.68 | KDM4E (0.47) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL17871022 | 0.68 | ALDH1A1 (0.36) | ALDH1A1MAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017207395-A1 | ISOTHIAZOLOPYRIDONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-07 | — | — | WO | disclosed |