Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.30 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.30 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9785476 | 0.78 | — | — | |
| SCHEMBL14724344 | 0.77 | SHBG (0.36) | SHBGKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13082486 | 0.77 | CYP4F2 (0.35) | HDAC1HDAC6SHBGPDCD1CD274 | |
| SCHEMBL11415512 | 0.74 | HDAC1 (0.37) | HDAC1HDAC6DPP4 | |
| SCHEMBL24012991 | 0.74 | HDAC1 (0.34) | HDAC1HDAC6SHBGALDH1A1HSD17B10 | |
| SCHEMBL12169249 | 0.74 | DPP4 (0.37) | DPP4 | |
| SCHEMBL4156564 | 0.74 | HDAC1 (0.31) | HDAC1HDAC6 | |
| SCHEMBL4621597 | 0.73 | PDCD1 (0.39) | KDM4EALDH1A1HPGDHSD17B10PDCD1 | |
| SCHEMBL4621767 | 0.73 | MAPK1 (0.36) | PDCD1CD274MAPK1MAP2K4MAPKAPK2 | |
| SCHEMBL11054959 | 0.72 | SHBG (0.41) | SHBGKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017208632-A1 | ESTER COMPOUND AND USE THEREOF | 大日本除蟲菊株式会社 | 2017-12-07 | — | — | WO | disclosed |