SCHEMBL4621767

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4621597	0.82	PDCD1 (0.39)	MAPK1MAP2K4MAPKAPK2MAPKAPK3MAPK6
	SCHEMBL14816144	0.82	PDCD1 (0.35)	MAPK1MAP2K4MAPKAPK2MAPKAPK3MAPK6
	SCHEMBL18899611	0.80	METAP2 (0.35)	PDCD1CD274METAP2CYP4F2CYP4A11
	SCHEMBL584538	0.79	CA2 (0.42)	RIPK1
	SCHEMBL11967063	0.79	RIPK1 (0.38)	RIPK1METAP2DAO
	SCHEMBL31670722	0.78	PDCD1 (0.33)	PDCD1CD274METAP2
	SCHEMBL31719921	0.78	PDCD1 (0.33)	MAPK1MAP2K4MAPKAPK2MAPKAPK3MAPK6
	SCHEMBL20562966	0.78	PDCD1 (0.33)	PDCD1CD274METAP2
	SCHEMBL8128078	0.78	PDCD1 (0.33)	PDCD1CD274METAP2
	SCHEMBL698604	0.78	CES2 (0.41)	MAPK1MAP2K4MAPKAPK2MAPKAPK3MAPK6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.