⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2565975 | 0.85 | — | — | |
| SCHEMBL19693019 | 0.79 | — | — | |
| SCHEMBL29492489 | 0.70 | P2RY2 (0.40) | — | |
| SCHEMBL29607435 | 0.69 | DUT (0.40) | — | |
| SCHEMBL19709266 | 0.69 | DUT (0.40) | — | |
| SCHEMBL19709264 | 0.69 | DUT (0.40) | — | |
| SCHEMBL17144041 | 0.66 | DUT (0.33) | — | |
| SCHEMBL31543054 | 0.65 | — | — | |
| SCHEMBL23313171 | 0.65 | P2RY2 (0.44) | — | |
| SCHEMBL20820770 | 0.64 | P2RY2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464313-A1 | 5'-CYCLO-PHOSPHONATE MODIFIED NUCLEOTIDES | Arrowhead Pharmaceuticals, Inc. (US) | 2019-04-10 | — | — | EP | disclosed |
| WO-2017214112-A1 | 5'-CYCLO-PHOSPHONATE MODIFIED NUCLEOTIDES | Arrowhead Pharmaceuticals, Inc. (US) | 2017-12-14 | — | — | WO | disclosed |