P-Hydroxycinnamaldehyde

P-Hydroxycinnamaldehyde

SCHEMBL196960

O=C/C=C/c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
KDM4E B2RXH2 3/20 1.00
MAPT P10636 3/20 1.00
APP P05067 4/20 0.68
XDH P47989 2/20 0.59
LMNA P02545 3/20 0.58
TRPA1 O75762 2/20 0.58
ALOX5 P09917 2/20 0.58
MAPK1 P28482 1/20 0.58
CCNB2 O95067 1/20 0.57
CDK1 P06493 1/20 0.57
CDK4 P11802 1/20 0.57
CCNB1 P14635 1/20 0.57
CCND1 P24385 1/20 0.57
CCNB3 Q8WWL7 1/20 0.57
ALDH5A1 P51649 1/20 0.56
ABAT P80404 1/20 0.56
TYR P14679 3/20 0.54
CYP2C9 P11712 3/20 0.54
CYP2D6 P10635 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Hydroxycinnamaldehyde SCHEMBL20912952 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EMAPTAPPXDH
P-Hydroxycinnamaldehyde SCHEMBL197453 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EMAPTAPPXDH
P-Hydroxycinnamaldehyde SCHEMBL28156217 0.98 ALDH1A1 (0.95) ALDH1A1KDM4EMAPTAPPXDH
P-Hydroxycinnamaldehyde SCHEMBL17296474 0.91 ALDH1A1 (0.83) ALDH1A1KDM4EMAPTAPPXDH
P-Hydroxycinnamaldehyde SCHEMBL17296476 0.91 ALDH1A1 (0.83) ALDH1A1KDM4EMAPTAPPXDH
P-Hydroxycinnamaldehyde SCHEMBL27582650 0.91 MAPT (0.83) ALDH1A1KDM4EMAPTAPPXDH
SCHEMBL15272541 0.91 ALDH1A1 (0.83) ALDH1A1KDM4EMAPTAPPXDH
SCHEMBL6194091 0.91 ALDH1A1 (0.83) ALDH1A1KDM4EMAPTAPPXDH
SCHEMBL19619423 0.88 MAPT (0.77) ALDH1A1KDM4EMAPTAPPXDH
SCHEMBL1310214 0.87 ALDH1A1 (0.75) ALDH1A1KDM4EMAPTAPPXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 775 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630758-B2 Downhole methods and compositions used in such DORF KETAL CHEMICALS FZE (AE) 2026-05-19 US claimed
EP-3500282-B1 AN ANTI-INFLAMMATORY COMPOSITION FOR THE TREATMENT OF ACUTE JOINT INFLAMMATION AND A PROCESS FOR PREPARATION THEREOF AUREA BIOLABS PRIVATE LTD (IN) 2026-03-18 EP claimed
US-12497557-B2 Methods for stimulating a hydrocarbon-bearing formation by perforating a wellbore and introducing an acidic composition in the wellbore DORF KETAL CHEMICALS FZE (AE) 2025-12-16 US claimed
CN-118667779-B Cyclo She Luoshuo cinnamyl alcohol dehydrogenase gene and application thereof 河北大学 2025-06-17 CN claimed
CN-119386098-B Composition for inhibiting uric acid formation and application thereof 佛山微奥云生物技术有限公司 2025-05-23 CN claimed
CN-120022331-A An antiinflammatory composition containing herba Ocimi extract and its preparation method 中山市中医院 2025-05-23 CN claimed
CN-119708403-A Resorcinol-cinnamaldehyde resin, its preparation method, modified vulcanized rubber composition and application 华奇(中国)化工有限公司 2025-03-28 CN claimed
US-12241021-B2 Method for fracking of simulation of hydrocarbon bearing formation DORF KETAL CHEMICALS FZE (AE) 2025-03-04 US claimed
CN-119505756-A Acrylic adhesive and preparation method thereof 湖南省和祥润新材料有限公司 2025-02-25 CN claimed
US-12234384-B2 Adhesion-improving composition for textile material and associated reinforcing textile material PORCHER INDUSTRIES (FR) 2025-02-25 US claimed
WO-1999063108-A1 NOVEL PEROXIDASE SUBSTRATES AND THEIR USE IN CATALYZED REPORTER DEPOSITION NEN LIFE SCIENCE PRODUCTS, INC. (US) 1999-12-09 WO claimed
US-5985242-A PEPTIDE OF 3 TO 5 D-AMINO ACIDS; MAY BE MODIFIED AT AMINO-AND/OR CARBOXY TERMINUS; FOR TREATMENT OF AMYLOIDOSIS, ALZHEIMER'S DISEASE PRAECIS PHARMACEUTICALS, INC. (US) 1999-11-16 US claimed
WO-1999053935-A1 NOVEL SYNERGISTIC COMPOSITIONS CONTAINING AROMATIC COMPOUNDS AND TERPENOIDS PRESENT IN ALPINIA GALANGA IDA DEVELOPMENT A/S (DK) 1999-10-28 WO claimed
EP-0929574-A1 MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS Praecis Pharmaceuticals Incorporated (US) 1999-07-21 EP claimed
EP-0581980-B1 3- and/or 4-substituted derivatives of quinic acid and process to prepare 3- and/or 4-substituted derivatives of quinic acid NESTLE SA (CH) 1999-03-03 EP claimed
US-5863748-A p-Hydroxycinnamoyl-containing substrates for an analyte dependent enzyme activation system NEW LIFE SCIENCE PRODUCTS, INC. (US) 1999-01-26 US claimed
WO-1998008868-A9 MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS 1998-05-28 WO claimed
WO-1998008868-A1 MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS PRAECIS PHARMACEUTICALS INCORPORATED (US) 1998-03-05 WO claimed
US-5401858-A Preparation of quinic acid derivatives NESTEC S.A. (CH) 1995-03-28 US claimed
EP-0581980-A1 3- and/or 4-substituted derivatives of quinic acid and process to prepare 3- and/or 4-substituted derivatives of quinic acid SOCIETE DES PRODUITS NESTLE S.A. (CH) 1994-02-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630758-B2 Downhole methods and compositions used in such IL1B, GET3, IL17A ALDH1A1 4815/4885KDM4E 4625/4885MAPT 4649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.