Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.63 |
| ▸ | LYN | P07948 | 4/20 | 0.63 |
| ▸ | LCK | P06239 | 4/20 | 0.63 |
| ▸ | EGFR | P00533 | 5/20 | 0.60 |
| ▸ | TEC | P42680 | 4/20 | 0.60 |
| ▸ | BMX | P51813 | 4/20 | 0.60 |
| ▸ | ITK | Q08881 | 3/20 | 0.60 |
| ▸ | SRC | P12931 | 3/20 | 0.60 |
| ▸ | ABL1 | P00519 | 2/20 | 0.60 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.60 |
| ▸ | FYN | P06241 | 2/20 | 0.60 |
| ▸ | YES1 | P07947 | 2/20 | 0.60 |
| ▸ | HCK | P08631 | 2/20 | 0.60 |
| ▸ | FGR | P09769 | 2/20 | 0.60 |
| ▸ | FER | P16591 | 2/20 | 0.60 |
| ▸ | CSK | P41240 | 2/20 | 0.60 |
| ▸ | BLK | P51451 | 2/20 | 0.60 |
| ▸ | JAK3 | P52333 | 2/20 | 0.60 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.60 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17065707 | 0.95 | BTK (0.65) | BTKLYNLCKEGFRTEC | |
| SCHEMBL22002211 | 0.86 | BTK (0.71) | BTKLYNLCKEGFRTEC | |
| SCHEMBL18335270 | 0.85 | BTK (0.77) | BTKLYNLCKEGFRTEC | |
| SCHEMBL18476813 | 0.85 | BTK (0.71) | BTKLYNLCKEGFRTEC | |
| SCHEMBL18131947 | 0.85 | BTK (0.71) | BTKLYNLCKEGFRTEC | |
| SCHEMBL19696813 | 0.81 | BTK (0.62) | BTKLYNLCKEGFRTEC | |
| SCHEMBL17065613 | 0.81 | BTK (0.78) | BTKLYNLCKEGFRTEC | |
| SCHEMBL19696890 | 0.80 | TGFBR1 (0.47) | EGFRITKSRCABL1HCK | |
| SCHEMBL17065632 | 0.80 | BTK (0.79) | BTKLYNLCKEGFRTEC | |
| SCHEMBL22243280 | 0.80 | BTK (0.76) | BTKLYNLCKEGFRTEC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840509-B2 | Heterocyclic compounds | CADILA HEALTHCARE LIMITED (IN) | 2017-12-12 | — | — | US | disclosed |