Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19997571 | 0.86 | OGG1 (0.49) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL10249607 | 0.82 | OGG1 (0.51) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL17032600 | 0.82 | OGG1 (0.54) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL21394757 | 0.79 | OGG1 (0.55) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL105734 | 0.77 | OGG1 (0.57) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL10549386 | 0.77 | OGG1 (0.50) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL9870144 | 0.77 | OGG1 (0.53) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL4192025 | 0.76 | OGG1 (0.49) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL19405290 | 0.76 | OGG1 (0.49) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL10451483 | 0.76 | OGG1 (0.56) | OGG1SLC6A4KMT2AGRM5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840481-B2 | Allosteric modulators of nicotinic acetylcholine receptors | MERCK SHARP & DOHME CORP. (US) | 2017-12-12 | — | — | US | disclosed |