Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21291152 | 0.90 | KDM4E (0.35) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL19697437 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL19697817 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL29334102 | 0.74 | KDM4E (0.40) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL19697838 | 0.71 | CYP4A11 (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL16388000 | 0.68 | CDK8 (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL16230568 | 0.68 | ACACB (0.55) | KDM4EALDH1A1 | |
| SCHEMBL19697398 | 0.67 | KDM4E (0.34) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL19697724 | 0.67 | KDM4E (0.34) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL19697836 | 0.66 | FBP1 (0.34) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214413-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS HISTONE DEMETHYLASE INHIBITORS | Chrysalis, Inc. (US) | 2017-12-14 | — | — | WO | disclosed |