Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.30 |
| ▸ | GLRB | P48167 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19697833 | 0.90 | KDM4E (0.35) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL19697437 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL19697817 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL29334102 | 0.74 | KDM4E (0.40) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL19697838 | 0.73 | CYP4A11 (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL5555517 | 0.69 | CA12 (0.46) | KDM4EALDH1A1HSD17B10TSHRGLRA3 | |
| SCHEMBL16388000 | 0.68 | CDK8 (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL19697398 | 0.67 | KDM4E (0.34) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL19697724 | 0.67 | KDM4E (0.34) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL19697836 | 0.66 | FBP1 (0.34) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190256509-A1 | HISTONE DEMETHYLASE INHIBITORS | CHRYSALIS INC (US) | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256509-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM6B, KDM2A | KDM4E 12/4885ALDH1A1 1564/4885HPGD 1945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.