Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12269525 | 0.90 | MEN1 (0.41) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL16843042 | 0.85 | HTT (0.44) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL820390 | 0.85 | HTT (0.44) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10021094 | 0.81 | MEN1 (0.41) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL15305874 | 0.81 | MEN1 (0.41) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL15305875 | 0.80 | TSHR (0.32) | THRBTSHR | |
| SCHEMBL28932843 | 0.79 | HTT (0.42) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10021095 | 0.79 | HTT (0.42) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL16263904 | 0.79 | HTT (0.42) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10992527 | 0.75 | THRB (0.56) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355830-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE COMPRISING TREAD FORMED FROM SAID RUBBER COMPOSITION | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2017-12-14 | — | — | US | disclosed |