Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL376004 | 0.89 | THRB (0.32) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL375472 | 0.89 | THRB (0.32) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL17322737 | 0.89 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL16843042 | 0.86 | HTT (0.44) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL19697948 | 0.85 | HTT (0.43) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL28419655 | 0.84 | ALDH1A1 (0.32) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL6567765 | 0.84 | ALDH1A1 (0.32) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL12269525 | 0.82 | MEN1 (0.41) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10021094 | 0.82 | MEN1 (0.41) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL375539 | 0.81 | ADRB2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233552-A1 | PLASTIC-COATED MERCAPTOSILANE/WAX MIXTURE | EVONIK DEGUSSA GMBH (DE) | 2017-08-17 | — | — | US | disclosed |
| US-9617287-B2 | Mercaptosilanes | EVONIK DEGUSSA GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9593228-B2 | Mixtures composed of functionalized diene rubbers with trimethylolpropane and fatty acid, a process for production thereof and use thereof | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-03-14 | — | — | US | disclosed |
| US-9512306-B2 | Mercaptosilane polymer mixture | EVONIK DEGUSSA GMBH (DE) | 2016-12-06 | — | — | US | disclosed |
| US-20150353734-A1 | MERCAPTOSILANE POLYMER MIXTURE | EVONIK OPERATIONS GMBH (DE) | 2015-12-10 | — | — | US | disclosed |
| US-20120270974-A1 | MIXTURES COMPOSED OF FUNCTIONALIZED DIENE RUBBERS WITH TRIMETHYLOLPROPANE AND FATTY ACID, A PROCESS FOR PRODUCTION THEREOF AND USE THEREOF | RHEIN CHEMIE RHEINAU GMBH (DE) | 2012-10-25 | — | — | US | disclosed |
| US-20110287205-A1 | Mercaptosilanes | EVONIK OPERATIONS GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| US-8013178-B2 | Mercaptosilanes and derivatives thereof | EVONIK DEGUSSA GMBH (DE) | 2011-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287205-A1 | Mercaptosilanes | MSR1, MSRB3, CCNE2 | HTT 3400/4885MEN1 962/4885THRB 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.