Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5836381 | 0.85 | KMT2A (0.46) | KMT2AALDH1A1MEN1MAPTTDP1 | |
| SCHEMBL27918598 | 0.78 | KMT2A (0.49) | KMT2AALDH1A1MEN1MAPTTDP1 | |
| SCHEMBL27647345 | 0.77 | ALDH1A1 (0.41) | KMT2AALDH1A1MEN1MAPTTDP1 | |
| SCHEMBL15142435 | 0.75 | KMT2A (0.50) | KMT2AALDH1A1MEN1MAPTTDP1 | |
| SCHEMBL6129965 | 0.75 | KMT2A (0.46) | KMT2AALDH1A1MEN1MAPTTDP1 | |
| SCHEMBL11118451 | 0.73 | ALDH1A1 (0.51) | KMT2AALDH1A1TDP1KDM4EBLM | |
| SCHEMBL4577407 | 0.73 | KMT2A (0.47) | KMT2AALDH1A1MEN1MAPTTDP1 | |
| SCHEMBL27733971 | 0.72 | KMT2A (0.47) | KMT2AALDH1A1MEN1MAPTTDP1 | |
| SCHEMBL9567928 | 0.71 | ALDH1A1 (0.36) | KMT2AALDH1A1MEN1MAPTTDP1 | |
| SCHEMBL7187367 | 0.71 | KMT2A (0.42) | KMT2AALDH1A1MEN1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334636-A2 | HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2011-06-22 | — | — | EP | disclosed |