Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL8965117 | 0.98 | L3MBTL1 (0.44) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL27918598 | 0.77 | KMT2A (0.49) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL8965109 | 0.76 | TSHR (0.49) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL6129965 | 0.74 | KMT2A (0.46) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL15142435 | 0.74 | KMT2A (0.50) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL7699172 | 0.74 | ALDH1A1 (0.50) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL10762043 | 0.74 | L3MBTL1 (0.36) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL2835326 | 0.74 | ALDH1A1 (0.50) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL7697891 | 0.72 | ALOX5 (0.43) | KMT2AALDH1A1MEN1MAPTL3MBTL1 | |
| SCHEMBL1969808 | 0.71 | KMT2A (0.44) | KMT2AALDH1A1MEN1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926134-B1 | Processes for producing alpha-cyanohydrin esters and alpha-hydroxy acids | DAICEL CHEM (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6111128-A | IN THE PRESENCE OF A METAL CATALYST, REACTING AN ENOL ESTER OF GIVEN FORMULA OR OXIME ESTER WITH A CARBONYL COMPOUND AND CYANOGENATION AGENT TO FORM AN ALPHA-CYANOHYDRIN ESTER WHICH IS HYDROLYZED TO FORM ALPHA-HYDROXY ACIDS; EFFICIENCY | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0926134-A2 | Processes for producing alpha-cyanohydrin esters and alpha-hydroxy acids | Daicel Chemical Industries, Ltd. (JP) | 1999-06-30 | — | — | EP | disclosed |