Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27558629 | 0.84 | MAPT (0.48) | MAPTTSHRRAB9ANPC1ALOX15 | |
| SCHEMBL14776689 | 0.84 | MAPT (0.41) | MAPTTSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL16762217 | 0.82 | MAPT (0.47) | MAPTTSHRRAB9ANPC1ALOX15 | |
| SCHEMBL2089912 | 0.80 | HSD17B10 (0.44) | MAPTTSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL2398385 | 0.78 | KMT2A (0.49) | MAPTTSHRRAB9ANPC1ALOX15 | |
| SCHEMBL3123406 | 0.78 | ALDH1A1 (0.67) | MAPTTSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL12930243 | 0.77 | NPC1 (0.57) | MAPTTSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL12109863 | 0.76 | NPC1 (0.49) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL9299954 | 0.75 | RAB9A (0.53) | MAPTTSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL23482163 | 0.73 | NPC1 (0.46) | MAPTTSHRRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017524-B2 | Compound and pharmaceutical composition for neuropsychological disorder or malignant tumor | KYOTO UNIVERSITY (JP) | 2018-07-10 | — | — | US | disclosed |
| US-20170355715-A1 | COMPOUND AND PHARMACEUTICAL COMPOSITION FOR NEUROPSYCHOLOGICAL DISORDER OR MALIGNANT TUMOR | KYOTO UNIVERSITY (JP) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355715-A1 | COMPOUND AND PHARMACEUTICAL COMPOSITION FOR NEUROPSYCHOLOGICAL DISORDER OR MALIGNANT TUMOR | VHL, TP53, COMT | MAPT 174/4885TSHR 4290/4885RAB9A 2200/4885 |
| US-10017524-B2 | Compound and pharmaceutical composition for neuropsychological disorder or malignant tumor | VHL, TP53, COMT | MAPT 174/4885TSHR 4290/4885RAB9A 2200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.