Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 15/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 14/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 14/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 14/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 14/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 14/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 14/20 | 0.59 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19690670 | 0.95 | HDAC8 (0.55) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL15076040 | 0.87 | HDAC3 (0.65) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL19690667 | 0.83 | HDAC8 (0.51) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL19690458 | 0.83 | HDAC8 (0.54) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL4214837 | 0.83 | TLR8 (0.57) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL23104953 | 0.83 | HDAC8 (0.46) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL4224259 | 0.82 | HDAC8 (0.61) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL16271201 | 0.82 | HDAC8 (0.61) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL2189376 | 0.82 | HDAC8 (0.61) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL16169650 | 0.82 | HDAC8 (0.50) | HDAC8HDAC6HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170358761-A1 | Luminescent Compounds and Methods of Using Same | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170358761-A1 | Luminescent Compounds and Methods of Using Same | CRY2, CYBA, TYR | HDAC8 4124/4885HDAC6 3500/4885HDAC3 3343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.