Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16271201 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL4224259 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6HDAC2HDAC3HDAC4 | |
| Bromide SCHEMBL1890168 | 0.98 | HDAC8 (0.60) | HDAC8HDAC6HDAC2HDAC3HDAC4 | |
| Bromide SCHEMBL1889733 | 0.98 | HDAC8 (0.60) | HDAC8HDAC6HDAC2HDAC3HDAC4 | |
| Bromide SCHEMBL1881301 | 0.98 | HDAC8 (0.60) | HDAC8HDAC6HDAC2HDAC3HDAC4 | |
| Bromide SCHEMBL1883444 | 0.98 | HDAC8 (0.60) | HDAC8HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL9991081 | 0.98 | HDAC8 (0.60) | HDAC8HDAC6HDAC2HDAC3HDAC4 | |
| Bromide SCHEMBL1888885 | 0.97 | L3MBTL1 (0.59) | HDAC8HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL12022150 | 0.94 | CYP19A1 (0.58) | HDAC8HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL12022152 | 0.87 | CYP19A1 (0.62) | HDAC8HDAC6HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112275322-B | Preparation method and application of supported CNTs @ NHC-Cu catalytic material | 中国科学院兰州化学物理研究所 | 2022-01-25 | — | — | CN | disclosed |
| US-20210163568-A1 | AZIDE INSULIN ANALOGUES | MERCK SHARP & DOHME CORP. (US) | 2021-06-03 | — | — | US | disclosed |
| CN-112275322-A | Preparation method and application of supported CNTs @ NHC-Cu catalytic material | 中国科学院兰州化学物理研究所 | 2021-01-29 | — | — | CN | disclosed |
| US-9375705-B2 | Heterogeneous copper nanocatalyst and manufacturing methods thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2016-06-28 | — | — | US | disclosed |
| US-8877676-B2 | Heterogeneous copper nanocatalyst and manufacturing methods thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2014-11-04 | — | — | US | disclosed |
| US-8877676-B2 | Heterogeneous copper nanocatalyst and manufacturing methods thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2014-11-04 | — | — | US | disclosed |
| US-20140302984-A1 | HETEROGENEOUS COPPER NANOCATALYST AND MANUFACTURING METHODS THEREOF | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2014-10-09 | — | — | US | disclosed |
| US-8563738-B2 | Ligands for copper-catalyzed azide-alkyne cycloaddition reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2013-10-22 | — | — | US | disclosed |
| US-20110172417-A1 | Heterogeneous Copper Nanocatalyst and Manufacturing Methods Thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2011-07-14 | — | — | US | disclosed |
| US-20100197871-A1 | LIGANDS FOR COPPER-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | THE SCRIPPS RESEARCH INSTITUTE | 2010-08-05 | — | — | US | disclosed |
| WO-2009038685-A1 | LIGANDS FOR COPPER-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163568-A1 | AZIDE INSULIN ANALOGUES | IAPP, INSR, GPR119 | HDAC8 3703/4885HDAC6 3374/4885HDAC2 4750/4885 |
| US-20110172417-A1 | Heterogeneous Copper Nanocatalyst and Manufacturing Methods Thereof | AOC3, AOC2, USP13 | HDAC8 4688/4885HDAC6 2486/4885HDAC2 3765/4885 |
| US-20100197871-A1 | LIGANDS FOR COPPER-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | AOC2, AOC1, AOC3 | HDAC8 3905/4885HDAC6 3697/4885HDAC2 2186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.