Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 4/20 | 0.59 |
| ▸ | FLT3 | P36888 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.57 |
| ▸ | CD74 | P04233 | 1/20 | 0.56 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12022166 | 0.88 | CYP19A1 (0.84) | CYP19A1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL19708172 | 0.84 | CYP19A1 (0.77) | CYP19A1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL79086 | 0.84 | HDAC3 (0.61) | CYP19A1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL935182 | 0.83 | CYP19A1 (1.00) | CYP19A1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL28585573 | 0.83 | CYP19A1 (0.74) | CYP19A1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL30991876 | 0.82 | CD74 (0.81) | CYP19A1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL29275461 | 0.82 | CD74 (0.81) | CYP19A1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL16050564 | 0.82 | CYP19A1 (0.72) | CYP19A1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL12037700 | 0.82 | CYP19A1 (0.68) | CYP19A1GSK3BFLT3NPC1RAB9A | |
| SCHEMBL29352717 | 0.82 | CYP19A1 (0.72) | CYP19A1HDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10461266-B2 | Luminescent compounds and methods of using same | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2019-10-29 | — | — | US | disclosed |
| US-20170358761-A1 | Luminescent Compounds and Methods of Using Same | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2017-12-14 | — | — | US | disclosed |
| US-20170358761-A1 | Luminescent Compounds and Methods of Using Same | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170358761-A1 | Luminescent Compounds and Methods of Using Same | CRY2, CYBA, TYR | CYP19A1 1582/4885HDAC3 3343/4885HDAC1 2390/4885 |
| US-10461266-B2 | Luminescent compounds and methods of using same | CRY2, CYBA, TYR | CYP19A1 1582/4885HDAC3 3343/4885HDAC1 2390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.