Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.59 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.50 |
| ▸ | DPP4 | P27487 | 7/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19700145 | 0.85 | KCNH2 (0.50) | KCNH2TMEM97SIGMAR1DPP9DPP8 | |
| SCHEMBL19700137 | 0.85 | KCNH2 (0.50) | KCNH2TMEM97SIGMAR1DPP9DPP8 | |
| SCHEMBL18999610 | 0.78 | DPP8 (0.39) | KCNH2TMEM97SIGMAR1DPP9DPP8 | |
| SCHEMBL13923531 | 0.77 | DPP7 (0.45) | KCNH2TMEM97SIGMAR1DPP4DPP7 | |
| SCHEMBL8228638 | 0.77 | DPP9 (0.47) | KCNH2TMEM97SIGMAR1DPP9DPP8 | |
| SCHEMBL17797706 | 0.76 | NR1H2 (0.44) | KCNH2TMEM97SIGMAR1DPP9DPP8 | |
| SCHEMBL26727548 | 0.76 | HTR2A (0.38) | KCNH2TMEM97SIGMAR1DPP4 | |
| SCHEMBL13112861 | 0.76 | ALDH1A1 (0.38) | KCNH2TMEM97SIGMAR1DPP7 | |
| SCHEMBL16978143 | 0.76 | TMEM97 (1.00) | KCNH2TMEM97SIGMAR1 | |
| SCHEMBL861946 | 0.73 | MAOA (0.44) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858900-B2 | Fluorinated 2-amino-4-(substituted amino)phenyl carbamate derivatives | OCUTERRA THERAPEUTICS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-11858900-B2 | Fluorinated 2-amino-4-(substituted amino)phenyl carbamate derivatives | OCUTERRA THERAPEUTICS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-11312722-B2 | Hsp90 inhibitors and uses thereof | TRUSTEES OF BOSTON UNIVERSITY (US) | 2022-04-26 | — | — | US | disclosed |
| US-20210309612-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | OCUTERRA THERAPEUTICS, INC. | 2021-10-07 | — | — | US | disclosed |
| US-20200354373-A1 | HSP90 INHIBITORS AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-11-12 | — | — | US | disclosed |
| US-20170355679-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SCIFLUOR LIFE SCIENCES, INC. | 2017-12-14 | — | — | US | disclosed |
| US-20170355679-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SCIFLUOR LIFE SCIENCES, INC. | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354373-A1 | HSP90 INHIBITORS AND USES THEREOF | HSP90AB1, HSP90B1, HSP90AA1 | KCNH2 4627/4885TMEM97 2014/4885SIGMAR1 4365/4885 |
| US-20170355679-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | KCNQ2, KCNQ1, KCNQ3 | KCNH2 15/4885TMEM97 1444/4885SIGMAR1 2397/4885 |
| US-11858900-B2 | Fluorinated 2-amino-4-(substituted amino)phenyl carbamate derivatives | KCNQ2, KCNQ1, KCNQ3 | KCNH2 15/4885TMEM97 1444/4885SIGMAR1 2397/4885 |
| US-20210309612-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | KCNQ2, KCNQ1, KCNQ3 | KCNH2 15/4885TMEM97 1444/4885SIGMAR1 2397/4885 |
| US-11312722-B2 | Hsp90 inhibitors and uses thereof | HSP90AB1, HSP90B1, HSP90AA1 | KCNH2 4627/4885TMEM97 2014/4885SIGMAR1 4365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.