Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 3/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19700456 | 0.74 | THRB (0.45) | ALDH1A1MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL19690883 | 0.73 | THRB (0.54) | ALDH1A1MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL5206965 | 0.72 | CNR2 (0.47) | CNR2LRRK2SRD5A2CES2ALDH1A1 | |
| SCHEMBL5207410 | 0.71 | CNR2 (0.46) | CNR2LRRK2SRD5A2CES2ALDH1A1 | |
| SCHEMBL16201993 | 0.70 | NOTUM (0.56) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL1237189 | 0.68 | SRD5A2 (0.79) | CNR2SRD5A2CES2ALDH1A1MEN1 | |
| SCHEMBL12918501 | 0.68 | MAPT (0.53) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL9165022 | 0.67 | SRD5A2 (0.55) | CNR2LRRK2SRD5A2CES2ALDH1A1 | |
| SCHEMBL17586586 | 0.66 | KCNK3 (0.67) | CNR2SRD5A2CES2ALDH1A1MEN1 | |
| SCHEMBL13719485 | 0.66 | IDH1 (0.51) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355708-A1 | POTASSIUM CHANNEL MODULATORS | CADENT THERAPEUTICS, INC. | 2017-12-14 | — | — | US | disclosed |
| US-20170355708-A1 | POTASSIUM CHANNEL MODULATORS | CADENT THERAPEUTICS, INC. | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355708-A1 | POTASSIUM CHANNEL MODULATORS | KCNJ11, KCNJ2, KCNJ1 | CNR2 1001/4885LRRK2 1184/4885SRD5A2 1542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.