Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 7/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206965 | 0.91 | CNR2 (0.47) | CNR2LRRK2VNN1SRD5A2MEN1 | |
| SCHEMBL5206266 | 0.78 | KCNQ3 (0.54) | CNR2VNN1SRD5A2MEN1ALDH1A1 | |
| SCHEMBL5203501 | 0.76 | CNR2 (0.51) | CNR2LRRK2VNN1SRD5A2MEN1 | |
| SCHEMBL19700515 | 0.71 | CNR2 (0.47) | CNR2LRRK2VNN1SRD5A2MEN1 | |
| SCHEMBL27443558 | 0.69 | MEN1 (0.52) | CNR2VNN1SRD5A2MEN1ALDH1A1 | |
| SCHEMBL5209985 | 0.67 | HSP90AA1 (0.39) | MEN1CYP1A2CYP3A4MAPTKMT2A | |
| SCHEMBL7873623 | 0.67 | ALDH1A1 (0.44) | MEN1ALDH1A1CYP1A2MAPTKMT2A | |
| SCHEMBL1237189 | 0.66 | SRD5A2 (0.79) | CNR2VNN1SRD5A2MEN1ALDH1A1 | |
| SCHEMBL9169211 | 0.66 | SRD5A2 (0.53) | CNR2LRRK2VNN1SRD5A2MEN1 | |
| SCHEMBL10765363 | 0.66 | ALDH1A1 (0.50) | CNR2LRRK2VNN1SRD5A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036066-B1 | SUBSTITUTED PYRIMIDINE AND PYRIDINE HERBICIDES | MID AMERICA COMMERCIALIZATION (US) | 2007-04-18 | — | — | EP | claimed |