Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851306 | 0.75 | ALDH1A1 (0.55) | MAPTALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL3576418 | 0.74 | KDM4E (0.51) | MAPTALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL2237187 | 0.73 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| Bromide SCHEMBL3576414 | 0.73 | KDM4E (0.50) | MAPTALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL2831481 | 0.68 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL2049182 | 0.68 | ALDH1A1 (0.65) | MAPTALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL28850677 | 0.67 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL30379991 | 0.67 | KMT2A (0.61) | MAPTALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL5180011 | 0.67 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL3864912 | 0.67 | KMT2A (0.61) | MAPTALDH1A1KDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214269-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INFINITY PHARMACEUTICALS, INC. (US) | 2017-12-14 | — | — | WO | disclosed |