Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.72 |
| ▸ | HTR2C | P28335 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10968736 | 0.96 | SRD5A2 (0.77) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL29666493 | 0.91 | SRD5A2 (0.75) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL17767361 | 0.91 | SRD5A2 (0.75) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL20198232 | 0.87 | SRD5A2 (0.64) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL2186803 | 0.85 | SRD5A2 (0.66) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL2188139 | 0.85 | SRD5A2 (0.66) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL30738988 | 0.85 | SRD5A2 (0.66) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL19225657 | 0.84 | SRD5A2 (0.60) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL22036983 | 0.84 | SRD5A2 (0.60) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL503767 | 0.84 | SRD5A2 (1.00) | SRD5A2HTR2CHTR2BDRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334630-A2 | CARBONYL DERIVATIVES HAVING A C3 SYMMETRY, THEIR PREPARATION AND USES THEREOF | Universita'Degli Studi di Roma "La Sapienza" (IT) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010038252-A2 | CARBONYL DERIVATIVES HAVING A C3 SYMMETRY, THEIR PREPARATION AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI ROMA LA SAPIENZA (IT) | 2010-04-08 | — | — | WO | disclosed |