SCHEMBL2186803

SCHEMBL2186803

O=C(c1ccccc1)c1ccc2c(c1)Cc1cc(C(=O)c3ccccc3)ccc1-2

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 3/20 0.66
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
MAPT P10636 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.57
ATM Q13315 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
CYP2C8 P10632 1/20 0.55
CYP2C9 P11712 1/20 0.55
ALDH1A1 P00352 2/20 0.54
SRD5A1 P18405 1/20 0.51
DRD2 P14416 1/20 0.51
ADRA1D P25100 1/20 0.51
HTR2A P28223 1/20 0.51
HTR2C P28335 1/20 0.51
HTR7 P34969 1/20 0.51
ADRA1A P35348 1/20 0.51
ADRA1B P35368 1/20 0.51
HTR2B P41595 1/20 0.51
PTPRC P08575 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30738988 1.00 SRD5A2 (0.66) SRD5A2NPC1RAB9AMAPTL3MBTL1
SCHEMBL2188139 1.00 SRD5A2 (0.66) SRD5A2NPC1RAB9AMAPTL3MBTL1
SCHEMBL29666493 0.95 SRD5A2 (0.75) SRD5A2NPC1RAB9AMAPTL3MBTL1
SCHEMBL17767361 0.95 SRD5A2 (0.75) SRD5A2NPC1RAB9AMAPTL3MBTL1
SCHEMBL10968736 0.89 SRD5A2 (0.77) SRD5A2NPC1RAB9AMAPTL3MBTL1
SCHEMBL29206750 0.86 SRD5A2 (0.51) SRD5A2NPC1RAB9AMAPTL3MBTL1
SCHEMBL30018122 0.86 SRD5A2 (0.51) SRD5A2NPC1RAB9AMAPTL3MBTL1
SCHEMBL1970132 0.85 SRD5A2 (0.72) SRD5A2NPC1RAB9AMAPTL3MBTL1
SCHEMBL29206739 0.85 SRD5A2 (0.50) SRD5A2NPC1RAB9AMAPTL3MBTL1
SCHEMBL30017270 0.85 SRD5A2 (0.50) SRD5A2NPC1RAB9AMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240010665-A1 NOVEL TRANSITION METAL COMPOUND, TRANSITION METAL CATALYST COMPOSITION CONTAINING THE SAME, AND METHOD FOR PRODUCING COPOLYMER OF ETHYLENE AND a-OLEFIN USING THE SAME HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2024-01-11 US disclosed
US-20240010665-A1 NOVEL TRANSITION METAL COMPOUND, TRANSITION METAL CATALYST COMPOSITION CONTAINING THE SAME, AND METHOD FOR PRODUCING COPOLYMER OF ETHYLENE AND a-OLEFIN USING THE SAME HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2024-01-11 US disclosed
EP-4303223-A1 NOVEL TRANSITION METAL COMPOUND, TRANSITION METAL CATALYST COMPOSITION CONTAINING THE SAME, AND METHOD FOR PRODUCING COPOLYMER OF ETHYLENE AND ALPHA-OLEFIN USING THE SAME Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2024-01-10 EP disclosed
CN-117343110-A Novel transition metal compound, catalyst composition containing the same, and method for producing ethylene and alpha-olefin copolymer using the same 韩华道达尔能源有限公司 2024-01-05 CN disclosed
EP-2342172-B1 BIFLUORENYLIDENE DERIVATIVES, THEIR PREPARATION AND USES THEREOF UNIV ROMA (IT) 2012-08-08 EP disclosed
EP-2342172-A1 BIFLUORENYLIDENE DERIVATIVES, THEIR PREPARATION AND USES THEREOF Università degli Studi di Roma "La Sapienza" (IT) 2011-07-13 EP disclosed
WO-2010038251-A1 BIFLUORENYLIDENE DERIVATIVES, THEIR PREPARATION AND USES THEREOF UNIVERSITÀ DEGLI STUDI DI ROMA LA SAPIENZA (IT) 2010-04-08 WO disclosed
WO-2009058396-A1 NEGATIVE BIREFRINGENT OPTICAL FILMS WITH FLAT OR REVERSED BIREFRINGENCE WAVELENGTH DISPERSIONS FOR LIQUID CRYSTAL DISPLAYS AKRON POLYMER SYSTEMS INC. (US) 2009-05-07 WO disclosed
EP-0666267-B1 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM CO (US) 2001-04-18 EP disclosed
CN-1060176-C Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM CO (US) 2001-01-03 CN disclosed
US-5571880-A CATALYSTS FOR POLYMERIZATION OF OLEFINS ESPECIALLY TO OBTAIN SYNDIOTACTIC POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1996-11-05 US disclosed
CN-1109472-A Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM CO (US) 1995-10-04 CN disclosed
EP-0666267-A2 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-08-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240010665-A1 NOVEL TRANSITION METAL COMPOUND, TRANSITION METAL CATALYST COMPOSITION CONTAINING THE SAME, AND METHOD FOR PRODUCING COPOLYMER OF ETHYLENE AND a-OLEFIN USING THE SAME NOTUM, ETFB, ETFA SRD5A2 1752/4885NPC1 3337/4885RAB9A 4427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.