SCHEMBL197014

SCHEMBL197014

CN(C)[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
ECE1 P42892 3/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
KMT2A Q03164 1/20 0.33
NOS2 P35228 2/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32
GRIK1 P39086 2/20 0.30
GRIK2 Q13002 1/20 0.30
GABRR1 P24046 2/20 0.30
SLC7A5 Q01650 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15274 1.00 TDP1 (0.35) TDP1ECE1ALOX15BLMPMP22
Trifluoroacetic Acid SCHEMBL28921331 0.88 NOS1 (0.33) NOS2NOS1
SCHEMBL10349045 0.83 TDP1 (0.37) TDP1ECE1CHRNB2CHRNB4CHRNA3
SCHEMBL149117 0.82 ECE1 (0.32) ECE1ALOX15BLMPMP22KMT2A
SCHEMBL28531439 0.82 ECE1 (0.32) ECE1ALOX15BLMPMP22KMT2A
SCHEMBL14393213 0.81 TDP1 (0.35) TDP1ALOX15BLMPMP22CHRNB2
SCHEMBL17772929 0.80 ECE1 (0.31) ECE1ALOX15BLMPMP22KMT2A
SCHEMBL6006627 0.80 TDP1 (0.43) TDP1GABRR1
SCHEMBL196267 0.80 TDP1 (0.43) TDP1GABRR1
SCHEMBL196268 0.80 TDP1 (0.43) TDP1GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115301218-B Lignocellulose sponge-based waste gas adsorption material and application thereof 江苏宿迁润泰环保科技有限公司 2024-03-08 CN claimed
CN-115301218-A Waste gas adsorbing material based on lignocellulose sponge and application thereof 江苏宿迁润泰环保科技有限公司 2022-11-08 CN claimed
US-20160244484-A1 ANTI-INFLAMMATORY TRIPEPTIDES DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2016-08-25 US claimed
EP-3049428-A1 ANTI-INFLAMMATORY TRIPEPTIDES Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) 2016-08-03 EP claimed
WO-2015040235-A1 ANTI-INFLAMMATORY TRIPEPTIDES DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2015-03-26 WO claimed
CN-118201966-A Human transferrin receptor binding antibody-peptide conjugates 肽梦想株式会社 2024-06-14 CN disclosed
CN-118159298-A Method for producing antibody-linker conjugates 阿拉里斯生物技术股份公司 2024-06-07 CN disclosed
CN-118055773-A Lipopeptides inhibitors of interleukin-23 receptor 詹森生物科技公司 2024-05-17 CN disclosed
CN-117980320-A Bicyclic peptide inhibitors of interleukin-23 receptor 詹森生物科技公司 2024-05-03 CN disclosed
CN-117957240-A Human transferrin receptor binding peptides 肽梦想株式会社 2024-04-30 CN disclosed
CN-115301218-B Lignocellulose sponge-based waste gas adsorption material and application thereof 江苏宿迁润泰环保科技有限公司 2024-03-08 CN disclosed
CN-116801910-A Means and methods for producing antibody-linker conjugates 阿拉里斯生物技术股份公司 2023-09-22 CN disclosed
WO-2006001499-A2 METASTIN DERIVATIVES AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-01-05 WO disclosed
EP-1554394-A2 ASPARAGINYL HYDROXYLASES AND MODULATORS THEREOF ISIS INNOVATION LIMITED (GB) 2005-07-20 EP disclosed
WO-2004035812-A2 ASPARAGINYL HYDROXYLASES AND MODULATORS THEREOF ISIS INNOVATION LIMITED (GB) 2004-04-29 WO disclosed
EP-0948523-B1 PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE BOEHRINGER INGELHEIM CA LTD (CA) 2004-03-17 EP disclosed
US-6333402-B1 FOR THERAPY AND DIAGNOSIS DYAX CORP. 2001-12-25 US disclosed
US-6057287-A KUNITZ DOMAIN HAVING DISULFIDE BONDS AT CYSTINE 5-55, 14-38, 30-51 POSITIONS DYAX CORP. (US) 2000-05-02 US disclosed
EP-0383190-B1 Ribonucleotide reductase inhibitors BIO MEGA BOEHRINGER INGELHEIM (CA) 1995-06-14 EP disclosed
EP-0438873-A1 Inhibitor of ribonucleotide reductase of herpes viruses MERCK & CO. INC. (US) 1991-07-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160244484-A1 ANTI-INFLAMMATORY TRIPEPTIDES VIP, TNF, ENPEP TDP1 2255/4885ECE1 352/4885ALOX15 478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.