Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19710833 | 0.82 | FASN (0.33) | SMN1; SMN2PDK2FASN | |
| SCHEMBL24767170 | 0.79 | CYP2D6 (0.33) | HRH3CYP2D6KCNH2FASN | |
| SCHEMBL19698027 | 0.78 | CHRNB2 (0.43) | HRH3CYP2D6KCNH2SMN1; SMN2 | |
| SCHEMBL10140407 | 0.77 | FASN (0.35) | PDK2FASN | |
| SCHEMBL20690383 | 0.77 | NR1H2 (0.47) | HRH3SMN1; SMN2 | |
| SCHEMBL20680690 | 0.77 | NR1H2 (0.47) | HRH3SMN1; SMN2 | |
| SCHEMBL20690384 | 0.77 | NR1H2 (0.47) | HRH3SMN1; SMN2 | |
| SCHEMBL21846683 | 0.76 | CHRNB2 (0.52) | SMN1; SMN2 | |
| SCHEMBL21541820 | 0.76 | SMN1; SMN2 (0.34) | HRH3SMN1; SMN2 | |
| SCHEMBL21541817 | 0.76 | SMN1; SMN2 (0.34) | HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355707-A1 | BICYCLIC HETEROARYL AMINE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-12-14 | — | — | US | disclosed |
| US-20170355707-A1 | BICYCLIC HETEROARYL AMINE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355707-A1 | BICYCLIC HETEROARYL AMINE COMPOUNDS | PIK3R3, JAK2, JAK3 | HRH3 61/4885CYP2D6 1976/4885KCNH2 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.