Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | USP9X | Q93008 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19702015 | 0.86 | NOTUM (0.50) | NOTUMKCNH2HRH3GRM2 | |
| SCHEMBL19702013 | 0.83 | BPTF (0.57) | NOTUMCHRNA7HRH3CHRNB2CHRNA4 | |
| SCHEMBL19702010 | 0.82 | NOTUM (0.50) | NOTUMUSP9XHRH3GRM2 | |
| SCHEMBL25752839 | 0.81 | NOTUM (0.55) | NOTUMKCNH2HRH3GRM2 | |
| SCHEMBL19702014 | 0.81 | NOTUM (0.49) | NOTUMHRH3GRM2 | |
| SCHEMBL19702012 | 0.81 | NOTUM (0.55) | NOTUMUSP9XHRH3 | |
| SCHEMBL26498532 | 0.81 | NOTUM (0.55) | NOTUMKCNH2HRH3GRM2 | |
| SCHEMBL26498531 | 0.81 | NOTUM (0.51) | NOTUMKCNH2HRH3GRM2 | |
| SCHEMBL29310100 | 0.80 | CHRNA7 (0.45) | CHRNA7KCNH2HRH3CHRNB2CHRNA4 | |
| SCHEMBL19702016 | 0.79 | NOTUM (0.47) | NOTUMUSP9XHRH3GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355707-A1 | BICYCLIC HETEROARYL AMINE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-12-14 | — | — | US | disclosed |
| US-20170355707-A1 | BICYCLIC HETEROARYL AMINE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355707-A1 | BICYCLIC HETEROARYL AMINE COMPOUNDS | PIK3R3, JAK2, JAK3 | NOTUM 3221/4885CHRNA7 1603/4885KCNH2 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.