Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17661012 | 0.81 | L3MBTL1 (0.41) | L3MBTL1MEN1KMT2AMGLLKDM4E | |
| SCHEMBL2879270 | 0.81 | MAPT (0.57) | CHRNA7CHRNB2CHRNA4L3MBTL1KCNH2 | |
| SCHEMBL22851866 | 0.81 | MAPT (0.57) | CHRNA7CHRNB2CHRNA4L3MBTL1KCNH2 | |
| SCHEMBL17660612 | 0.80 | ALDH1A1 (0.43) | L3MBTL1MEN1KMT2AMGLLKDM4E | |
| SCHEMBL19702011 | 0.80 | NOTUM (0.51) | CHRNA7CHRNB2CHRNA4KCNH2HRH3 | |
| SCHEMBL23544861 | 0.79 | L3MBTL1 (0.46) | L3MBTL1MEN1KMT2AMGLLKDM4E | |
| SCHEMBL14923974 | 0.79 | L3MBTL1 (0.46) | L3MBTL1MEN1KMT2AMGLLKDM4E | |
| SCHEMBL23544859 | 0.79 | L3MBTL1 (0.46) | L3MBTL1MEN1KMT2AMGLLKDM4E | |
| SCHEMBL27389306 | 0.79 | CHRNA7 (0.49) | CHRNA7CHRNB2CHRNA4KCNH2MEN1 | |
| SCHEMBL20867677 | 0.78 | MEN1 (0.38) | L3MBTL1KCNH2MEN1KMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228459-A1 | WEE1 INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. | 2024-07-11 | — | — | US | disclosed |
| US-20240228459-A1 | WEE1 INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228459-A1 | WEE1 INHIBITORS AND USES THEREOF | WEE1, WEE2, DCLRE1B | CHRNA7 4854/4885CHRNB2 4712/4885CHRNA4 4862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.