⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18215044 | 1.00 | — | — | |
| SCHEMBL7699865 | 0.92 | — | — | |
| SCHEMBL686346 | 0.92 | — | — | |
| SCHEMBL15153587 | 0.90 | GPR84 (0.45) | — | |
| SCHEMBL5353579 | 0.90 | GPR84 (0.45) | — | |
| SCHEMBL686971 | 0.90 | GPR84 (0.45) | — | |
| SCHEMBL5353586 | 0.90 | GPR84 (0.45) | — | |
| SCHEMBL11116040 | 0.90 | GPR84 (0.45) | — | |
| SCHEMBL8845886 | 0.90 | GPR84 (0.45) | — | |
| SCHEMBL8179839 | 0.90 | GPR84 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326702-A | Hydrolysis of the nitrile | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-07-05 | — | — | US | claimed |
| US-4085275-A | Production of di-unsaturated carboxylic acids | MONSANTO COMPANY (US) | 1978-04-18 | — | — | US | claimed |
| CN-119192025-A | Industrial preparation method and application of alpha-hydroxynitrile | 哈尔滨理工大学 | 2024-12-27 | — | — | CN | disclosed |
| US-9128238-B2 | Optical material and molded product thereof | MITSUI CHEMICALS, INC. (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20130030136-A1 | OPTICAL MATERIAL AND MOLDED PRODUCT THEREOF | MITSUI CHEMICALS, INC. (JP) | 2013-01-31 | — | — | US | disclosed |
| EP-1730291-B1 | NITRILE HYDRATASE OF RHODOCOCCUS | EVONIK DEGUSSA GMBH (DE) | 2012-12-05 | — | — | EP | disclosed |
| EP-1730177-B1 | CYANIDE TOLERANT NITRILHYDRATASES | EVONIK DEGUSSA GMBH (DE) | 2012-02-29 | — | — | EP | disclosed |
| US-8088613-B2 | Nitrilases, nucleic acids encoding them and methods for making and using them | VERENIUM CORPORATION (US) | 2012-01-03 | — | — | US | disclosed |
| US-7943359-B2 | Polynucleotides which code for cyanide-tolerant nitrile hydratase and compositions thereof | EVONIK DEGUSSA GMBH (DE) | 2011-05-17 | — | — | US | disclosed |
| US-20100261250-A1 | Cyanide-Tolerant Nitrile Hydratases | OSSWALD STEFFEN | 2010-10-14 | — | — | US | disclosed |
| EP-1308518-B2 | Method of producing carboxylic acids | DAICEL CHEM (JP) | 2010-09-22 | — | — | EP | disclosed |
| WO-1996023753-A1 | IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |
| EP-0711836-A1 | Method of producing optically active alpha-hydroxy acid or alpha-hydroxyamide | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5326702-A | Hydrolysis of the nitrile | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0486289-A2 | Biological process for producing alpha-hydroxyamide or alpha-hydroxy acid | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |
| US-4904812-A | Preparation of unsaturated nitriles | BASF AKTIENGESELLSCHAFT (DE) | 1990-02-27 | — | — | US | disclosed |
| EP-0340797-A2 | Curable polymer composition | Kanegafuchi Chemical Industry Co., Ltd. (JP) | 1989-11-08 | — | — | EP | disclosed |
| US-4511562-A | (Thio)(dithio-phosphates(phosphonates), processes for their preparation, and their use in pest-combating agents | BAYER AKTIENGESELLSCHAFT (DE) | 1985-04-16 | — | — | US | disclosed |
| US-4486600-A | Process for the production of β-hydroxy-α-aminocarboxylic acids | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-12-04 | — | — | US | disclosed |
| US-4085275-A | Production of di-unsaturated carboxylic acids | MONSANTO COMPANY (US) | 1978-04-18 | — | — | US | disclosed |