Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20930972 | 0.82 | GABRA1 (0.38) | TAAR1GABRA1GABRG2GABRB3GABRB2 | |
| SCHEMBL16746090 | 0.78 | MEN1 (0.36) | MEN1ALDH1A1GAAKMT2AINMT | |
| SCHEMBL24427304 | 0.73 | MEN1 (0.48) | MEN1ALDH1A1GAAKMT2ANISCH | |
| SCHEMBL19359819 | 0.69 | GABRA1 (0.39) | GABRA1GABRG2GABRB3GABRB2FAAH | |
| SCHEMBL3419324 | 0.69 | NOTUM (0.40) | TAAR1GABRA1GABRG2GABRB3GABRB2 | |
| SCHEMBL16744209 | 0.69 | MEN1 (0.44) | MEN1ALDH1A1GAAKMT2AINMT | |
| SCHEMBL69988 | 0.69 | TAAR1 (0.40) | ALDH1A1GAATAAR1GABRA1GABRG2 | |
| SCHEMBL71450 | 0.68 | GABRA1 (0.38) | TAAR1GABRA1GABRG2GABRB3GABRB2 | |
| SCHEMBL1549125 | 0.67 | ALOX5 (0.42) | MEN1ALDH1A1GAAKMT2ACA1 | |
| SCHEMBL4705985 | 0.67 | CNR2 (0.45) | MEN1ALDH1A1GAAKMT2AINMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023534-B2 | Carbazole and tetrahydrocarbazole compounds useful as inhibitors of BTK | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170355673-A1 | TRICYCLIC ATROPISOMER COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355673-A1 | TRICYCLIC ATROPISOMER COMPOUNDS | BTK, LCK, SYK | MEN1 1960/4885ALDH1A1 4447/4885GAA 1607/4885 |
| US-10023534-B2 | Carbazole and tetrahydrocarbazole compounds useful as inhibitors of BTK | BTK, JAK2, SYK | MEN1 2482/4885ALDH1A1 4292/4885GAA 3343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.