Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2674786 | 0.90 | — | — | |
| SCHEMBL4265506 | 0.77 | SLC6A12 (0.37) | HPGD | |
| SCHEMBL11610955 | 0.75 | KMT2A (0.34) | HPGD | |
| SCHEMBL27854272 | 0.75 | HPGD (0.31) | HPGD | |
| SCHEMBL604515 | 0.75 | SLC6A12 (0.36) | HPGD | |
| SCHEMBL2561552 | 0.75 | — | — | |
| SCHEMBL14744489 | 0.75 | — | — | |
| SCHEMBL14744490 | 0.75 | — | — | |
| SCHEMBL19744067 | 0.73 | LMNA (0.36) | HPGD | |
| Potassium Ion SCHEMBL3267698 | 0.73 | HPGD (0.30) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334657-A1 | PIPERAZINE D3 AND 5-HT2A RECEPTOR MODULATORS | F. Hoffmann-La Roche AG (CH) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010031735-A1 | PIPERAZINE D3 AND 5-HT2A RECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-25 | — | — | WO | disclosed |