Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584209 | 0.84 | PKM (0.55) | PKMKMT2AGPR84SMN1; SMN2CYP1A2 | |
| SCHEMBL6190684 | 0.83 | PKM (0.56) | PKMKMT2AGPR84SMN1; SMN2CYP1A2 | |
| SCHEMBL6287075 | 0.83 | KMT2A (0.58) | PKMKMT2AGPR84SMN1; SMN2CYP1A2 | |
| SCHEMBL6287071 | 0.83 | PKM (0.56) | PKMKMT2AGPR84SMN1; SMN2CYP1A2 | |
| SCHEMBL31458574 | 0.83 | PKM (0.56) | PKMKMT2AGPR84SMN1; SMN2CYP1A2 | |
| SCHEMBL28034598 | 0.82 | PKM (0.55) | PKMKMT2AGPR84SMN1; SMN2CYP1A2 | |
| SCHEMBL27836199 | 0.82 | PKM (0.55) | PKMKMT2AGPR84SMN1; SMN2CYP1A2 | |
| SCHEMBL2404630 | 0.82 | HTR4 (0.43) | PKMKMT2AGPR84SMN1; SMN2FFAR1 | |
| SCHEMBL21176844 | 0.81 | PKM (0.49) | PKMKMT2AGPR84SMN1; SMN2CYP1A2 | |
| SCHEMBL14542028 | 0.81 | HTR2A (0.54) | PKMKMT2AGPR84SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334643-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | Actelion Pharmaceuticals Ltd. (CH) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | disclosed |