Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19692412 | 0.78 | LMNA (0.41) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL29536823 | 0.67 | MAPT (0.70) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL144590 | 0.67 | MAPT (0.70) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL245970 | 0.67 | LMNA (0.37) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL2984594 | 0.66 | LMNA (0.47) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| Hydrochloric Acid SCHEMBL11811816 | 0.66 | MAPT (0.68) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL1243375 | 0.65 | CYP3A4 (0.47) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL12266517 | 0.65 | LMNA (0.60) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL2671644 | 0.64 | PLAU (0.59) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL30527962 | 0.64 | PLAU (0.59) | LMNACYP3A4MAPTAPEX1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017211760-A1 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2017-12-14 | — | — | WO | disclosed |