Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.48 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 3/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
| ▸ | IL1B | P01584 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22857769 | 0.87 | CRBN (0.46) | CRBNDDB1IKZF3HDAC3HDAC1 | |
| SCHEMBL21906782 | 0.82 | CRBN (0.46) | CRBNDDB1IKZF3HDAC3HDAC1 | |
| SCHEMBL20759933 | 0.81 | CRBN (0.45) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL21897792 | 0.81 | CRBN (0.46) | CRBNDDB1IKZF3 | |
| SCHEMBL22959814 | 0.81 | S1PR5 (0.40) | S1PR5 | |
| SCHEMBL19709449 | 0.81 | CRBN (0.52) | CRBNDDB1IKZF3HDAC3HDAC1 | |
| SCHEMBL19541974 | 0.81 | CRBN (0.49) | CRBNDDB1IKZF3HDAC3HDAC1 | |
| SCHEMBL22243534 | 0.81 | CRBN (0.56) | CRBNDDB1IKZF3HDAC3HDAC1 | |
| SCHEMBL24123477 | 0.80 | CRBN (0.71) | CRBNDDB1IKZF3HDAC3HDAC1 | |
| SCHEMBL20990626 | 0.79 | CRBN (0.42) | CRBNDDB1IKZF3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268229-A1 | PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE | 和径医药科技（上海）有限公司 | 2022-12-29 | — | — | WO | disclosed |