Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | SELL | P14151 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28400880 | 0.81 | MEN1 (0.45) | HDAC8HDAC6 | |
| SCHEMBL31383411 | 0.78 | IAPP (0.55) | — | |
| SCHEMBL22982305 | 0.76 | SELL (0.44) | SELLSELP | |
| SCHEMBL31618870 | 0.76 | SELL (0.44) | SELLSELP | |
| SCHEMBL31383406 | 0.74 | IAPP (0.53) | — | |
| SCHEMBL19692985 | 0.73 | ERCC1 (0.44) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL28475321 | 0.70 | SELL (0.45) | SELLSELP | |
| SCHEMBL31632680 | 0.70 | SELL (0.41) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL26293601 | 0.70 | SELL (0.41) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL28467454 | 0.70 | IAPP (0.49) | SELLSELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017213897-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | CEDARS-SINAI MEDICAL CENTER (US) | 2017-12-14 | — | — | WO | disclosed |