Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 3/20 | 0.38 |
| ▸ | FPR2 | P25090 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 3/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.37 |
| ▸ | MC4R | P32245 | 2/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.37 |
| ▸ | MC1R | Q01726 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1969199 | 0.92 | TACR1 (0.42) | — | |
| SCHEMBL1972469 | 0.89 | TACR1 (0.41) | MAPTUBE2MDCUN1D1CXCR3XBP1 | |
| SCHEMBL1970589 | 0.89 | TACR1 (0.41) | MAPTUBE2MDCUN1D1CXCR3XBP1 | |
| SCHEMBL1968873 | 0.89 | TACR1 (0.41) | MAPTUBE2MDCUN1D1CXCR3XBP1 | |
| SCHEMBL2217579 | 0.85 | MAPT (0.38) | MAPTP2RX1UBE2MDCUN1D1CXCR3 | |
| SCHEMBL1970827 | 0.85 | TACR2 (0.38) | MAPTP2RX1TMPRSS4UBE2MDCUN1D1 | |
| SCHEMBL1966863 | 0.83 | KDR (0.38) | FPR2MAPTTMPRSS4UBE2MDCUN1D1 | |
| SCHEMBL1968062 | 0.83 | UBE2M (0.38) | FPR2MAPTUBE2MDCUN1D1XBP1 | |
| SCHEMBL1969884 | 0.81 | MCHR1 (0.38) | MAPTUBE2MDCUN1D1CXCR3EPHX2 | |
| SCHEMBL1970104 | 0.81 | MCHR1 (0.38) | MAPTUBE2MDCUN1D1CXCR3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178060-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE OF SAME | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-07-21 | — | — | US | disclosed |
| EP-2336105-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE OF SAME | Takeda Pharmaceutical Company Limited (JP) | 2011-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178060-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE OF SAME | NTSR2, BDKRB1, AVPR1B | FPR1 76/4885FPR2 89/4885MAPT 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.