Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 8/20 | 0.37 |
| ▸ | TACR2 | P21452 | 7/20 | 0.37 |
| ▸ | TAC3 | Q9UHF0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 2/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1969884 | 1.00 | MCHR1 (0.38) | MCHR1TACR1TACR2TAC3MAPT | |
| SCHEMBL2217579 | 0.88 | MAPT (0.38) | MAPTCXCR3DCUN1D1EPHX2UBE2M | |
| SCHEMBL1968873 | 0.88 | TACR1 (0.41) | TACR1MAPTTACR3CXCR3DCUN1D1 | |
| SCHEMBL1970589 | 0.88 | TACR1 (0.41) | TACR1MAPTTACR3CXCR3DCUN1D1 | |
| SCHEMBL1972469 | 0.88 | TACR1 (0.41) | TACR1MAPTTACR3CXCR3DCUN1D1 | |
| SCHEMBL1968062 | 0.86 | UBE2M (0.38) | TACR1MAPTTACR3DCUN1D1UBE2M | |
| SCHEMBL1966863 | 0.82 | KDR (0.38) | TACR1MAPTTACR3DCUN1D1UBE2M | |
| SCHEMBL1971127 | 0.81 | FPR1 (0.38) | MAPTCXCR3DCUN1D1EPHX2UBE2M | |
| SCHEMBL1969199 | 0.80 | TACR1 (0.42) | TACR1 | |
| SCHEMBL1973524 | 0.79 | MEN1 (0.37) | MAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178060-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE OF SAME | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-07-21 | — | — | US | disclosed |
| EP-2336105-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE OF SAME | Takeda Pharmaceutical Company Limited (JP) | 2011-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178060-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE OF SAME | NTSR2, BDKRB1, AVPR1B | MCHR1 136/4885TACR1 13/4885TACR2 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.