SCHEMBL197117

SCHEMBL197117

CC(C)(C)CC(N)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.48
PTGS1 P23219 2/20 0.46
SLC7A11 Q9UPY5 1/20 0.46
GRIK1 P39086 7/20 0.45
SLC1A2 P43004 7/20 0.43
SLC1A3 P43003 6/20 0.43
SLC1A1 P43005 6/20 0.43
GRIK2 Q13002 5/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
GRM8 O00222 1/20 0.42
GRM6 O15303 1/20 0.42
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GSR P00390 1/20 0.42
CYP1A2 P05177 1/20 0.42
GRM5 P41594 1/20 0.42
GRIA1 P42261 1/20 0.42
GRIA2 P42262 1/20 0.42
GRIA3 P42263 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197139 1.00 SLC7A5 (0.48) SLC7A5PTGS1SLC7A11GRIK1SLC1A2
SCHEMBL196695 1.00 SLC7A5 (0.48) SLC7A5PTGS1SLC7A11GRIK1SLC1A2
Ammonia Solution, Strong SCHEMBL28728215 0.97 SLC7A5 (0.46) SLC7A5PTGS1SLC7A11GRIK1SLC1A2
Hydrochloric Acid SCHEMBL21059082 0.97 SLC7A5 (0.46) SLC7A5PTGS1SLC7A11GRIK1SLC1A2
Chloromethane SCHEMBL29259265 0.97 SLC7A5 (0.46) SLC7A5PTGS1SLC7A11GRIK1SLC1A2
Hydrochloric Acid SCHEMBL28431532 0.97 SLC7A5 (0.46) SLC7A5PTGS1SLC7A11GRIK1SLC1A2
Hydrochloric Acid SCHEMBL18770586 0.97 SLC7A5 (0.46) SLC7A5PTGS1SLC7A11GRIK1SLC1A2
Trifluoroacetic Acid SCHEMBL4576488 0.89 GRB2 (0.42) SLC7A5PTGS1SLC7A11GRIK1SLC1A2
Trifluoroacetic Acid SCHEMBL27695113 0.89 GRB2 (0.42) SLC7A5PTGS1SLC7A11GRIK1SLC1A2
Leucine SCHEMBL9119565 0.87 SLC7A5 (0.72) SLC7A5GRIK1SLC1A2SLC1A3SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 743 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117529489-A Bicyclic peptide ligands specific for NK cells 拜斯科技术开发有限公司 2024-02-06 CN claimed
US-20240010684-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2024-01-11 US claimed
EP-4240750-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF Bayer Aktiengesellschaft (DE) 2023-09-13 EP claimed
CN-115957294-A Beneficial effects of supplementation with N-acetylcysteine and glycine to improve glutathione levels 贝勒医学院 2023-04-14 CN claimed
CN-115572237-A Preparation method of L-alpha-neopentyl glycine 苏州爱玛特生物科技有限公司 2023-01-06 CN claimed
EP-4011904-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF Bayer Aktiengesellschaft (DE) 2022-06-15 EP claimed
WO-2022096394-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2022-05-12 WO claimed
WO-2022080385-A1 PEPTIDE, AND MODIFICATION OF ANTIBODY WITH PEPTIDE 国立大学法人京都大学 2022-04-21 WO claimed
EP-3966226-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF Bayer Aktiengesellschaft (DE) 2022-03-16 EP claimed
EP-3752174-A1 FIBROBLAST GROWTH FACTOR ANALOGS AND USES THEREOF University of Florida Research Foundation, Incorporated (US) 2020-12-23 EP claimed
US-6255286-B1 CENTRAL NERVOUS SYSTEM DISORDERS; ALZHEIMER'S DISEASE NISSHIN FLOUR MILLING CO., LTD. (JP) 2001-07-03 US claimed
US-6252041-B1 Depsipeptides containing non-natural amino acids NISSHIN FLOUR MILLING CO., LTD. (JP) 2001-06-26 US claimed
US-6211145-B1 PRODUCTION OF APOLYPOPROTEIN E NISSHIN FLOUR MILLING CO., LTD. (JP) 2001-04-03 US claimed
EP-0967222-A1 CYCLIC DEPSIPEPTIDES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT Nisshin Flour Milling Co., Ltd. (JP) 1999-12-29 EP claimed
US-6001815-A ALZHEIMER'S DISEASE; ANTILIPEMIC AGENT NISSHIN FLOUR MILLING CO., LTD. (JP) 1999-12-14 US claimed
EP-0960885-A1 DEPSIPEPTIDES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT Nisshin Flour Milling Co., Ltd. (JP) 1999-12-01 EP claimed
EP-0934952-A2 Peptides containing an N-substituted glycine residue Nisshin Flour Milling Co., Ltd. (JP) 1999-08-11 EP claimed
EP-0931792-A1 Depsipeptides containing non-natural amino acids Nisshin Flour Milling Co., Ltd. (JP) 1999-07-28 EP claimed
EP-0927723-A1 Bicyclic depsipeptides promoting the production of apolipoprotein E Nisshin Flour Milling Co., Ltd. (JP) 1999-07-07 EP claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240010684-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF MASP2, SPINT2, SERPINB1 SLC7A5 3190/4885PTGS1 1400/4885SLC7A11 3749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.