SCHEMBL19711983

SCHEMBL19711983

CCSc1c(C(=O)N(C)OC)nc2cc(C(F)(F)F)ccn12

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 1/20 0.35
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 2/20 0.34
MLYCD O95822 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TRPA1 O75762 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.32
AKT1 P31749 1/20 0.31
AKT2 P31751 1/20 0.31
GFER P55789 2/20 0.31
POLB P06746 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HCRTR1 O43613 1/20 0.30
HCRTR2 O43614 1/20 0.30
GRIN2B Q13224 1/20 0.30
ALOX5 P09917 1/20 0.30
KCNN4 O15554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20765235 0.85 KDM4E (0.46) USP7ALDH1A1KDM4ESMN1; SMN2HSD17B10
SCHEMBL19711920 0.83 USP7 (0.39) USP7ALDH1A1KDM4ESMN1; SMN2HSD17B10
SCHEMBL19712036 0.83 USP7 (0.39) USP7ALDH1A1KDM4ESMN1; SMN2HSD17B10
SCHEMBL20781347 0.82 USP7 (0.41) USP7ALDH1A1KDM4ESMN1; SMN2HSD17B10
SCHEMBL19711966 0.82 USP7 (0.39) USP7ALDH1A1KDM4ESMN1; SMN2HSD17B10
Hydrochloric Acid SCHEMBL19711967 0.82 USP7 (0.39) USP7ALDH1A1KDM4ESMN1; SMN2HSD17B10
SCHEMBL19711996 0.82 PTGS1 (0.42) ALDH1A1KDM4ESMN1; SMN2HSD17B10POLB
SCHEMBL20636712 0.75 MLYCD (0.34) ALDH1A1MLYCDPTGDR2GFERGRIN2B
SCHEMBL20781338 0.75 USP7 (0.40) USP7ALDH1A1KDM4ESMN1; SMN2HSD17B10
SCHEMBL19712030 0.74 USP7 (0.40) USP7ALDH1A1KDM4ESMN1; SMN2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3257853-B1 CONDENSED HETEROCYCLIC COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT NISSAN CHEMICAL CORP (JP) 2021-11-10 EP disclosed
US-20210017194-A1 CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES NISSAN CHEMICAL CORPORATION (JP) 2021-01-21 US disclosed
US-10882869-B2 Condensed heterocyclic compounds and pesticides NISSAN CHEMICAL CORPORATION (JP) 2021-01-05 US disclosed
US-10464950-B2 Condensed heterocyclic compounds and pesticides NISSAN CHEMICAL CORPORATION (JP) 2019-11-05 US disclosed
US-20180022760-A1 CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-01-25 US disclosed
EP-3257853-A1 CONDENSED HETEROCYCLIC COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT Nissan Chemical Industries, Ltd. (JP) 2017-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180022760-A1 CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES HDAC3, CHRM3, NR1D2 USP7 4156/4885ALDH1A1 1228/4885KDM4E 3586/4885
US-10882869-B2 Condensed heterocyclic compounds and pesticides CNPY3, CNPY2, CHRM1 USP7 3940/4885ALDH1A1 3334/4885KDM4E 2522/4885
US-20210017194-A1 CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES HDAC3, CHRM3, NR1D2 USP7 4156/4885ALDH1A1 1228/4885KDM4E 3586/4885
US-10464950-B2 Condensed heterocyclic compounds and pesticides HDAC3, CHRM3, NR1D2 USP7 4156/4885ALDH1A1 1228/4885KDM4E 3586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.