Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.91 |
| ▸ | LCK | P06239 | 1/20 | 0.91 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.81 |
| ▸ | NPY1R | P25929 | 2/20 | 0.49 |
| ▸ | NPY2R | P49146 | 2/20 | 0.49 |
| ▸ | NPY4R | P50391 | 2/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.47 |
| ▸ | VEGFA | P15692 | 6/20 | 0.46 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | BECN1 | Q14457 | 3/20 | 0.44 |
| ▸ | TCF4 | P15884 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25547820 | 0.97 | EGFR (0.97) | EGFRLCKHKDC1NPY1RNPY2R | |
| Bacitracin SCHEMBL29603422 | 0.95 | EGFR (1.00) | EGFRLCKHKDC1NPY1RNPY2R | |
| Bacitracin SCHEMBL20385900 | 0.95 | EGFR (1.00) | EGFRLCKHKDC1NPY1RNPY2R | |
| Bacitracin SCHEMBL30071019 | 0.90 | HKDC1 (1.00) | EGFRLCKHKDC1NPY1RNPY2R | |
| SCHEMBL20375805 | 0.89 | EGFR (0.78) | EGFRLCKHKDC1NPY1RNPY2R | |
| SCHEMBL1024602 | 0.88 | EGFR (0.86) | EGFRLCKHKDC1NPY1RNPY2R | |
| SCHEMBL2274 | 0.88 | EGFR (0.86) | EGFRLCKHKDC1NPY1RNPY2R | |
| SCHEMBL4352461 | 0.88 | EGFR (0.86) | EGFRLCKHKDC1NPY1RNPY2R | |
| Bacitracin SCHEMBL12652843 | 0.87 | EGFR (0.85) | EGFRLCKHKDC1NPY1RNPY2R | |
| SCHEMBL29542898 | 0.86 | EGFR (0.76) | EGFRLCKHKDC1NPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257863-A1 | FLOUROUS METABOLICALLY STABLE PEPTIDE ANALOGS | Université de Strasbourg (FR) | 2017-12-20 | — | — | EP | disclosed |